The T-virus unleashed by the evil Umbrella corporation has spread to every corner of the globe, turning Earth into a hellscape of zombies, demons and monsters. Now Alice, a former Umbrella employee turned rogue warrior, joins her friends on a last-chance mission to save mankind by storming the company's headquarters located deep underneath what used to be Raccoon City. But the Red Queen knows Alice is coming, and the final battle will determine if the rest of mankind lives or dies.