Determined to keep Annabelle from wreaking havoc, demonologists Ed and Lorraine Warren bring the possessed doll to the locked artifacts room in their house, placing her ''safely'' behind sacred glass and enlisting a priest's holy blessing. But an unholy nigh of horror awaits as Annabelle awakens the evil spirits in the room, who all set their sights on a new target - the Warren's ten-year-old daughter, Judy, and her best friends.